High Yield Dermpath Bodies and Cells Part 4

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High Yield Dermpath Bodies and Cells Part 4

High Yield Dermpath Bodies and Cells Part 4 includes malakoplakia, which can have von Hansemann cells and Michaelis Gutmann bodies that represent calcified phagolysosomes containing incompletely digested bacteria, typically E. Coli, and highlight with von Kossa stain due to calcification. The sketch also covers Miescher microgranulomas seen in erythema nodosum as radial histiocytic aggregates in subcutaneous fat septa; Russell bodies, which are intracytoplasmic immunoglobulin accumulations in plasma cells; and Mikulicz cells in rhinoscleroma caused by Klebsiella rhinoscleromatis. It also covers mulberry cells of hibernomas, a benign tumor of brown fat composed of multivacuolated eosinophilic adipocytes most often arising on the neck and upper back in adults.

Malakoplakia

  • Van Handyman = Dense granulomatous infiltrate composed of von Hansemann cells
  • Cage And Pink And Blue Man = Large macrophages with eosinophilic cytoplasm which contains
  • Michael With Big Gut = Michaelis Gutmann bodies
  • Rounded Fat = Round laminated basophilic intracytoplasmic inclusions
  • Spilled Milk = Calcified
  • Spilled E Cola = Comprised of incompletely killed bacteria within calcified phagolysosomes
  • Van For Casas = Stain with von Kossa
  • Licking A Plate = Malakoplakia

Erythema Nodosum

  • Micro Grandma Mice = Miescher microgranulomas
  • White Star With Pink Purple Surrounding Ball = Radial histiocytic aggregates surrounding a central stellate cleft
  • Holding Pan Handle = Located in SQ fat septa
  • Shin Guards = Erythema nodosum

Rhinoscleroma And Related Cells

  • Michael Holding A Jar Of Pink Eyes = Mikulicz cells large foamy vacuolated histiocytes containing bacteria
  • Rhino With A Club = Klebsiella rhinoscleromatis gram negative rods
  • Russell Wilson = Russell bodies
  • Jar Of Pale Purple Marbles = Intracytoplasmic immunoglobulin collections eosinophilic stuffing the cytoplasm of plasma cells
  • Next To Rhino = Rhinoscleroma
  • English Grandma = Granuloma inguinale
  • Mulberry = Mulberry cells

Hibernoma

  • Hibernating Brown Bear = Seen in hibernomas tumor of brown fat
  • On The Neck And Upper Back = Most common in adults on the neck and upper back
  • Pink Red = Large pink red colored fat cells with a central nucleus and multivacuolated granular eosinophilic cytoplasm